statistics colloquium
Event Type:
Colloquium
Speaker:
Dr. Tim Hanson
Event Date:
Friday, March 11, 2016 -
3:30pm to 5:00pm
Location:
SMLC120
Audience:
General PublicFaculty/StaffStudentsAlumni/Friends
Sponsor/s:
Stats group
Event Description:
Title: Assessment of DPOAE Test-Retest Difference Curves via Hierarchical Gaussian Processes
Abstract: Distortion product otoacoustic emissions (DPOAE) testing is a promising alternative
to behavioral hearing tests and auditory brainstem response testing of pediatric
cancer patients. The central goal of this study is to assess whether significant
changes in the DPOAE frequency/emissions curve (DP-gram) occur in pediatric patients
in a test-retest scenario. This is accomplished through the construction of normal
reference charts, or credible regions, that DP-gram differences lie in, as well as
contour probabilities that measure how abnormal (or in a certain sense rare) a
test-retest difference is. A challenge is that the data were collected over varying
frequencies, at different time points from baseline, and on possibly one or both
ears. A hierarchical structural equation Gaussian process model is proposed to
handle the different sources of correlation in the emissions measurements, wherein
both subject-specific random effects and variance components governing the
smoothness and variability of each child's Gaussian process are coupled together.
